Figure 5From: One-step selection of Vaccinia virus-binding DNA aptamers by MonoLEXAntiviral activity of A38 against various OPV. OPV were propagated in cell culture in presence or absence of A38 as described above. The degree of infection in comparison to a positive control in the absence of A38 was determined by enumerating the number of infected cells (IFA, black bars), quantification of intracellular poxvirus DNA by real-time PCR (red bars) or determination of the poxvirus titer in the corresponding supernatant (green bars).Back to article page