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Figure 4 | BMC Biotechnology

Figure 4

From: Pore forming polyalkylpyridinium salts from marine sponges versus synthetic lipofection systems: distinct tools for intracellular delivery of cDNA and siRNA

Figure 4

Temperature sensitivity of poly-APS actions. A, dose/response relationship for poly-APS-evoked Ca2+ transients at room temperature (21°C, filled squares) and at 12°C (filled triangles). At each concentration of poly-APS, larger responses were obtained at the lower temperature. The different n values reflect variable sensitivities of HEK 293 cells to poly-APS with cells being more sensitive at lower temperatures. B, an example record showing larger increases in intracellular Ca2+ (Fl.R Fluorescence Ratio units) in response to poly-APS at 12°C compared with 21°C.

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