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Figure 6 | BMC Biotechnology

Figure 6

From: Modulation of 5' splice site selection using tailed oligonucleotides carrying splicing signals

Figure 6

Sequence of the oligonucleotides. The sequence in bold indicates complementarity to the region 4 to 23 nt upstream of the Bcl-xL 5' splice site. Boxed sequences contain the hnRNP A1 high-affinity binding sites UAGGGA and UAGGGU. The mutations in M4A1M are underlined. The underlined sequence in M4B5, M4B3, B3, and M4-25C corresponds to a human β-globin branch site sequence, while the double underlined sequence represents a β-globin 5' splice site sequence.

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