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Table 3 Effects of hazel and yew medium extracts on mitotic index and metaphase/anaphase transition

From: In vitro cell cultures obtained from different explants of Corylus avellanaproduce Taxol and taxanes

 

Mitotic index

Anaphases/metaphases no./no.

p*

Control

0.015 ± 0.01

0.189 ± 0.10

-

Taxol (10 nM)

0.040 ± 0.02

0.028 ± 0.02

<0.001

Hazel extract

0.065 ± 0.02

0.007 ± 0.01

<0.001

Yew extract

0.017 ± 0.01

0.071 ± 0.01

<0.01

  1. Data are the mean ± SD of at least 3 experiments. For each experiment at least 1000 interphase nuclei and 50 mitosis were counted.
  2. *p value estimates of significance by Fisher's exact test on anaphase/metaphase ratio.
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BMC Biotechnology

ISSN: 1472-6750

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