Skip to main content

Table 1 Alignment of amino acid sequence of envelope region of various single and double antigen fusion proteins.

From: Bifunctional recombinant fusion proteins for rapid detection of antibodies to both HIV-1 and HIV-2 in whole blood

Protein

AMINO ACID SEQUENCES OF HIV-1 and HIV-2 ANTIGENS FUSED AT THE C-TERMINUS OF Fd

 

Fd------- -------ENV1S/C-------------LINKER L-----------------ENV2S/C----------------cmyc

Fd

NASG

Fdenv1S

NASGVERYLKDQQLLGIWGSSGKLISTTAVPWNAS----------------------------------------------EQKLISEEDLN

Fdenv1C

NASGVERYLKDQQLLGIWGCSGKLICTTAVPWNAS----------------------------------------------EQKLISEEDLN

Fdenv2S

NASG------------------------------------------ AIEKYLQDQARLNSWGSAFRQVSHTTVPWVNGASEQKLISEEDLN

Fdenv2C

NASG------------------------------------------ AIEKYLQDQARLNSWGCAFRQVCHTTVPWVNGASEQKLISEEDLN

Fdenv12SS

NASGVERYLKDQQLLGIWGSSGKLISTTAVPWSNASGGGSGGGASGAIEKYLQDQARLNSWGSAFRQVSHTTVPWVNGASEQKLISEEDLN

Fdenv12CC

NASGVERYLKDQQLLGIWGCSGKLICTTAVPWSNASGGGSGGGASGAIEKYLQDQARLNSWGCAFRQVCHTTVPWVNGASEQKLISEEDLN

Fdenv12CS

NASGVERYLKDQQLLGIWGCSGKLICTTAVPWSNASGGGSGGGASGAIEKYLQDQARLNSWGSAFRQVSHTTVPWVNGASEQKLISEEDLN

Fdenv12SC

NASGVERYLKDQQLLGIWGSSGKLISTTAVPWSNASGGGSGGGASGAIEKYLQDQARLNSWGCAFRQVCHTTVPWVNGASEQKLISEEDLN

  1. Amino acids are shown in single letter code with Serine (S) and Cysteine (C) in bold letters. The linker is shown in bold letters. Various proteins are shown diagrammatically in Fig. 2.
Back to article page

BMC Biotechnology

ISSN: 1472-6750

Contact us