Figure 5From: Efficient generation of double heterologous promoter controlled oncolytic adenovirus vectors by a single homologous recombination step in Escherichia coliAnti-neoplastic efficacy of adenoviruses. HT-29 xenografts were grown subcutaneously to volumes of ~200 mm3. Groups of mice (n = 8) were treated with indicated adenoviruses by intratumoral injection of 5 × 109 virus particles in 100 μl PBS on day 0 and day 2. Tumors were measured at indicated time points and calculated volumes (mean ± SD) are presented as growth curves.Back to article page