Figure 4
From: Conditional gene expression in the mouse using a Sleeping Beautygene-trap transposon
T2/GT3/tTA gene disruptions and tissue-specific activation of a tet-responsive transgene in vivo A). T2/GT3/tTA insertions into mouse genes not linked to the original donor site. The genes are shown in the orientation of transcription with vertical lines as exons (from left to right) with the position and orientation of the IRES-tTA trapping cassette (arrow). B) Luciferase assays performed on individual tissues from four independent 02A-0002; Tg(tetL)1Bjd/J doubly transgenic and control Tg(tetL)1Bjd/J mice.