Figure 5
From: Reversible inactivation of the transcriptional function of P53 protein by farnesylation
Proportion of cells expressing markers of apoptosis 48 hr post transduction with the adenoviral vectors. Samples of cells were stained with annexin V-FITC 48 hr post transduction to detect externalized phosphatidylserine. Apoptosis in expressing cells was quantitated by FITC staining, counting 20 random microscopic fields. One representative experiment from a total of three is shown. Percentage of apoptotic cells was determined microscopically. Values are the means +/- SD of three different experiments.