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Table 2 Comparison of luminescence of tibial cranial muscles after electrotransfer of a luciferase-encoding plasmid and injection of luciferin i.p. (2.5 mg or 6 mg) or locally (0.1 mg)

From: Optical imaging of luminescence for in vivoquantification of gene electrotransfer in mouse muscle and knee

Luciferin administration i.p. local
  2.5 mg 6 mg 0.1 mg
Luminescence 105 units/min 2.05 ± 0.32 7.06 ± 2.79 18.42 ± 2.68
  1. Values are mean ± SEM (n = 6 to 12) of the integrated values of luminescence in ROI of the tibial cranial muscle 3 days after electrotransfer of 3 μg of pC1 luc plasmid as measured in vivo after luciferin injection i.p. (2.5 mg/250 μl, n = 6 or 6 mg/250 μl, n = 6) or locally (0.1 mg/40 μl n = 12). Local injection of luciferin was performed 2 hours or more after the i.p. injection. Background luminescence was subtracted from the luminescence measured.