| |
Ruc
|
p53
|
K-Ras
|
Smad4
|
β-CAT-Δ1
|
c-Myc
|
---|
Controls
|
1
|
194
|
19,319
|
480
|
10,582
|
269
|
4,752
|
|
2
|
9
|
9,830
|
1,064
|
3,575
|
835
|
2,913
|
|
3
|
8
|
5,236
|
445
|
1,773
|
211
|
2,006
|
|
4
|
38
|
3,187
|
477
|
1,919
|
530
|
1,831
|
|
5
|
14
|
11,908
|
795
|
6,884
|
161
|
3,346
|
|
6
|
31
|
5,390
|
823
|
1,724
|
235
|
2,050
|
|
7
|
76
|
22,526
|
1,909
|
6,996
|
259
|
11,816
|
|
8
|
29
|
15,338
|
943
|
8,043
|
445
|
3,475
|
|
9
|
10
|
12,282
|
1,162
|
19,380
|
215
|
3,623
|
|
10
|
9
|
11,130
|
1,109
|
4,429
|
501
|
5,060
|
+ 3 SDb
| |
214
|
30,234
|
2,237
|
22,788
|
997
|
12,874
|
Head and Neck
|
11
|
0
|
10,904
|
508
|
2,721
|
196
|
2,193
|
|
12
|
0
|
31,593
c
|
738
|
4,822
|
465
|
3,801
|
|
13
|
0
|
12,367
|
840
|
1,868
|
673
|
4,407
|
|
14
|
13
|
14,705
|
1,012
|
5,666
|
195
|
1,837
|
|
15
|
33
|
31,733
c
|
1,189
|
5,264
|
552
|
4,107
|
|
16
|
121
|
4,828
|
621
|
980
|
279
|
1,974
|
|
17
|
0
|
8,517
|
1,160
|
8,396
|
336
|
2,958
|
|
18
|
0
|
19,240
|
1,283
|
9,485
|
327
|
1,814
|
|
19
|
0
|
11,224
|
1,517
|
4,454
|
410
|
4,370
|
|
20
|
28
|
7,322
|
554
|
2,261
|
723
|
2,343
|
Breast
|
21
|
44
|
13,211
|
960
|
10,219
|
308
|
5,988
|
|
22
|
10
|
18,814
|
696
|
42,970
c
|
302
|
5,450
|
|
23
|
38
|
14,598
|
608
|
8,484
|
339
|
4,336
|
|
24
|
77
|
11,587
|
1,655
|
17,297
|
2363
c
|
3,431
|
|
25
|
17
|
19,954
|
532
|
10,184
|
772
|
15,650
c
|
|
26
|
25
|
9,538
|
195
|
5,962
|
300
|
1,646
|
|
27
|
10
|
7,815
|
2,561
c
|
20,628
|
426
|
3,524
|
|
28
|
21
|
15,607
|
308
|
7,380
|
284
|
1,579
|
|
29
|
0
|
18,058
|
160
|
6,790
|
304
|
2,333
|
|
30
|
245
c
|
25,479
|
1,919
|
9,727
|
495
|
3,787
|
Colon
|
31
|
4
|
6,656
|
1,204
|
3,252
|
267
|
1,763
|
|
32
|
40
|
20,928
|
4,293
c
|
5,567
|
962
|
6,143
|
|
33
|
42
|
34,703
c
|
1,472
|
10,830
|
716
|
4,906
|
|
34
|
51
|
300,943
c
|
6,439
c
|
2,610
|
992
|
3,789
|
|
35
|
35
|
5,670
|
3,306
c
|
3,860
|
477
|
1,772
|
|
36
|
44
|
6,516
|
695
|
37,344
c
|
371
|
2,395
|
- aSera, FLAG-Ruc-fusion extracts, protein A/G beads and buffer were mixed together, incubated for 60 minutes and processed. The data, light units, is the average of two experiments and is corrected for background (beads plus extract, but no sera). The standard deviation for each value is also available (see Additional file 1).
- bValues of the averages of the 10 control sera plus 3 standard deviations.
- cNumbers in bold are statistically significant: greater than the average plus 3 standard deviations of the 10 control sera.