Table 1 Genotype concordance and failure rates for MDA compared with gDNA across genotyping platforms.
Genotype Concordance Rate (%) | Genotype Failure Rate (%) | |||||
|---|---|---|---|---|---|---|
Genotyping Platform | Site of MDA production | Number of SNPs | Number of non-excluded samples | gDNA and MDA product template | gDNA template | MDA product template |
TaqMan | MSI | 95 | 88 | 99.71 | 2.4 | 4.0 |
TaqMan | In-house | 2 | 448 | 99.4 | 0.7 | 1.9 |
BeadArray | MSI | 345 | 77 | 98.8 | 0.06 | 0.2 |
Invader | MSI | 13 | 88 | 99.9 | 0.9 | 2.6 |