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Table 1 Relative in vitro splicing activity of constructs containing anti-theophylline aptamers. Extent of reaction is relative to the parental construct in 3 mM MgCl2 with no theophylline at 2 hrs.

From: Group I aptazymes as genetic regulatory switches

[Mg Cl2] 3 mM 8 mM
[Theo] 1.5 mM 0 mM 1.5 mM 0 mM
Parental 0.85 1 0.61 0.68
B11 0.03 0.02 0.31 0.34
Th1P6 0.2 0.05 0.31 0.16
Th2P6 0.15 0.04 0.31 0.04
Th3P6 0.03 0.04 0.2 0.04
Th4P6 0.06 0.05 0.38 0.37
Th5P6 0.04 0 0.05 0.03
Th6P6 0.03 0.01 0 0.03
Th1P5 1.08 0.91 0.85 0.74
Th1P5 0.03 0.03 0.7 0.57