Skip to main content

Advertisement

Figure 6 | BMC Biotechnology

Figure 6

From: Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratios

Figure 6

Effect of partial DAP substitution on the variability and magnitude of differential expression ratios. (A and B) CVs of the ratios plotted as a function of the mean ratio for unmodified (A) and modified (B) samples. Signal outliers, defined as any pair of signals which were greater than two-fold different in intensity, were removed from all samples. (C) Plot showing the number of probes having a designated CV across a range of CVs for control and partially DAP-modified cRNA targets. (D) Plot showing the number of probes having a designated fold change (ratio) across a range of ratios for control and partially DAP-modified cRNA targets.

Back to article page