Figure 6From: Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratiosEffect of partial DAP substitution on the variability and magnitude of differential expression ratios. (A and B) CVs of the ratios plotted as a function of the mean ratio for unmodified (A) and modified (B) samples. Signal outliers, defined as any pair of signals which were greater than two-fold different in intensity, were removed from all samples. (C) Plot showing the number of probes having a designated CV across a range of CVs for control and partially DAP-modified cRNA targets. (D) Plot showing the number of probes having a designated fold change (ratio) across a range of ratios for control and partially DAP-modified cRNA targets.Back to article page