Table 1 Overview of SH2 domain constructs included in this study
From: Solubility of recombinant Src homology 2 domains expressed in E. colican be predicted by TANGO
Short name | Construct | Gene | Accession number | Species | Start aa | End aa | C-terminal vector derived sequence | Construct total length (aa) |
|---|---|---|---|---|---|---|---|---|
1-TD | TSAd-67-207-IVTD | SH2D2A | NP_003966 | H sapiens | S67 | S207 | IVTD | 145 |
2-TD | TSAd-90-207-IVTD | SH2D2A | NP_003966 | H sapiens | G90 | S207 | IVTD | 122 |
3-RD | TSAd-67-188-PHRD | SH2D2A | NP_003966 | H sapiens | S67 | R188 | PHRD | 126 |
4-AS | TSAd-81-193-PAAS | SH2D2A | NP_003966 | H sapiens | T81 | P193 | PAAS | 117 |
5-RD | TSAd-90-188-PHRD | SH2D2A | NP_003966 | H sapiens | G90 | R188 | PHRD | 103 |
5-AS | TSAd-90-188-PAAS | SH2D2A | NP_003966 | H sapiens | G90 | R188 | PAAS | 103 |
mTSAd | mTSAd-111-210-AAAS | SH2D2A | NP_001020742 | M musculus | K111 | R210 | AAAS | 104 |
rTSAd | rTSAd-111-209-AAAS | SH2D2A | NP_997488 | R norvegicus | R111 | R209 | AAAS | 103 |
ALX | ALX-31-126-RPHRD | HSH2 | NP_116244 | H sapiens | G30 | R126 | RPHRD | 101 |
Lck | Lck-124-228-RPHRD | Lck | NP_005347 | H sapiens | P124 | K228 | RPHRD | 110 |