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Figure 1 | BMC Biotechnology

Figure 1

From: Optimization of heterologous protein production in Chinese hamster ovary cells under overexpression of spliced form of human X-box binding protein

Figure 1

Schematic representation of the DOX-regulated T-Rex™ overexpression XBP-1(s) system. The overproduction of IgG as a result of the XBP-1(s) overexpression and ER size expansion under DOX induction (on DOX induction) (A). The repression of XBP-1(s) overexpression and ER size expansion resulted in the repression of overproduction of IgG in the absence of DOX (off DOX induction) (B).

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BMC Biotechnology

ISSN: 1472-6750

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