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Table 2 The mTOR-related genes with at least a 1.5-fold change in expression level (P-values < 0.05)

From: The relationship between mTOR signalling pathway and recombinant antibody productivity in CHO cell lines

Gene symbol

Description

Fold change

P-value

Pik3cd

Phosphatidylinositol 3-kinase catalytic delta polypeptide

(+) 71.33

0.02

Pik3cg

Phosphoinositide-3-kinase, catalytic, gamma polypeptide

(+) 6.59

<0.001

Pld1

Phospholipase D1

(+) 4.63

0.02

Rragc

Ras-related GTP binding C

(+) 3.08

0.05

Ins2

Insulin II

(+) 3.06

0.02

Telo2

TEL2, telomere maintenance 2, homolog (S. cerevisiae)

(+) 2.44

0.01

Rps6

Ribosomal protein S6

(+) 1.89

0.05

Prkab1

Protein kinase, AMP-activated, beta 1 non-catalytic subunit

(+) 1.71

0.02