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Figure 6 | BMC Biotechnology

Figure 6

From: Dynamic strain scanning optimization: an efficient strain design strategy for balanced yield, titer, and productivity. DySScO strategy for strain design

Figure 6

The performance of the succinate-producing strains in fed-batch. (A-D) The consolidated strain performance (A), succinate yield (B), volumetric productivity(C), and titer (D) of both the hypothetical flux distributions and the designed strains in fed-batch simulations. The red dotted line indicates the range of growth rates selected for the static strain design process. The simulations assume the implementation of an ideal feeding strategy where the glucose concentration is maintained at 20 mM until the reactor is full. (E) The tradeoff between the succinate yield and the volumetric productivity. The Pareto frontier is outlined by the dotted line connecting the hypothetical flux distributions.

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BMC Biotechnology

ISSN: 1472-6750

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