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Table 1 Properties of HA variants

From: Towards a novel influenza vaccine: engineering of hemagglutinin on a platform of adenovirus dodecahedron

 

WWHA_1

HAWW_2

WWHA_3

HAWW_4

HAWW_5

WWHA_6

WW position

N-term

C-term

N-term

C-term

C-term

N-term

Deletion

  

SP, TM, CT

SP, TM. CT

TM, CT

SP

Solubility

  

+

+

++

 

Hemadsorption

 

+

  

+

 

Hemagglutination

 

+

  

+

 

Surface expression

+

++

++

++

+++

-

Interaction with Dd (overlay)

+

+

+

+

+

+

Interaction with Dd (ELISA)

-

-

-

-

+

-