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Table 5 Variation of the cloning outcome depending on different nuclear donor cell sources

From: Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set

Cell source1 Fusion rate (%) Chance for pregnancy Chance for delivery Cloning efficiency (%) No. of live cloned piglets No. of healthy cloned piglets
MSC 93.0 1.1 5.3 3.5 1.6 0.3
PF 80.2* 0.7 4.0 4.1 2.0 0.5
FF 89.1* 1.8 3.7* 4.4 3.4* 1.9*
KC 90.4* 1.3 2.9* 3.8 3.4* 1.4*
  1. Mesenchymal stem cells (MSC) were used as the reference category. For details on the statistical analysis and definition of the cloning benchmarks listed, please see Methods.
  2. * Statistically significant differences (p < 0.05).
  3. 1 Mesenchymal stem cells (MSC), postnatal fibroblasts (PF), fetal fibroblasts (FF), and kidney cells (KC).