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Table 4 Variation of the cloning outcome depending on the type of genetic modification

From: Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set

Genetic modification1 Chance for pregnancy Chance for delivery Cloning efficiency (%) No. of live cloned piglets No. of healthy cloned piglets
HR 1 4 3.8 2.3 0.6
AGT 1.8 6.2 4.2 3.5* 1.5*
Replication of transgenic pigs 1 2.4 3.9 2.7 1.2
  1. Homologous recombination (HR) was used as the reference category. For details on the statistical analysis and definition of the cloning benchmarks listed, please see Methods.
  2. * Statistically significant differences (p < 0.05).
  3. 1HR: homologous recombination, AGT: additive gene transfer, Replication of transgenic pigs: replication of already existing transgenic pig lines.
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BMC Biotechnology

ISSN: 1472-6750

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