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Table 4 Variation of the cloning outcome depending on the type of genetic modification

From: Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set

Genetic modification1

Chance for pregnancy

Chance for delivery

Cloning efficiency (%)

No. of live cloned piglets

No. of healthy cloned piglets

HR

1

4

3.8

2.3

0.6

AGT

1.8

6.2

4.2

3.5*

1.5*

Replication of transgenic pigs

1

2.4

3.9

2.7

1.2

  1. Homologous recombination (HR) was used as the reference category. For details on the statistical analysis and definition of the cloning benchmarks listed, please see Methods.
  2. * Statistically significant differences (p < 0.05).
  3. 1HR: homologous recombination, AGT: additive gene transfer, Replication of transgenic pigs: replication of already existing transgenic pig lines.