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Table 4 Comparison of tyrosinase production in batch and fed-batch cultures

From: High level production of tyrosinase in recombinant Escherichia coli

 

Cultivation time (h)

ODmax

Vol. activity of tyrosinase (U mL-1)

Yield of tyrosinase (g L-1)

Vol. productivity of tyrosinase (mg L-1 h-1)

Vol. act. of tyrosinase per time (mU mL-1 h-1)

Shake flask (Batch)

24

10.0 ± 0.9

0.76 ± 0.06

0.17 ± 0.01

7.1 ± 0.4

31.7 ± 2.5

Bioreactor (Fed-batch)

28

102.0 ± 2.0

13.00 ± 2.18

2.89 ± 0.48

103.2 ± 17.1

464.3 ± 77.8