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Figure 4 | BMC Biotechnology

Figure 4

From: Large-scale cell production of stem cells for clinical application using the automated cell processing machine

Figure 4

Global analysis of gene expression and genomic DNA mutations. (A) Comparison of array comparative genomic hybridization analysis. Human gDNA (from RAA) was compared to gDNA extracted from CSCs cultivated using AutoCulture® after 1 and 2 weeks using CGH arrays (arrays G4413A). (B) Microarray analysis of gene expression profiles. The pairwise scatter plot presents differences in gene expression on day 7 after seeding between manually cultured CSCs and those cultured using AutoCulture®. Grey dots represent transcripts with a subthreshold difference in expression. Red or green dots indicate those with at least a 3-fold difference in expression levels between the two groups. Gene expression levels are depicted on a log2 scale. The number of differentially expressed genes is indicated above.

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