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Table 5 Overview of different Staphylokinase expression systems published to date

From: Expression of recombinant staphylokinase in the methylotrophic yeast Hansenula polymorpha

No Expression system SAK Productivity [mg/Lbroth] Cultivation system Volume [L] SAK - glycosylation [Yes/No] Reference
1 E. coli > 50 (not defined) 2.7 No [8]
2 E. coli > 175 Fermenter 10-15 No [19]
3a B. subtilis 140 Shake flask 0.25 No [20]
3b B. subtilis 337 Fermenter 2 No [20]
4a P.pastoris 110 Fermenter < 5 Partially yes [13]
4b E. coli 300-400 Shake flask 0.1 No [13]
5 E. coli 2800 Fermenter 2 No [21]
6 P.pastoris ~ 1000 Shake flask (w/o -tunicamycin) 0.05 Yes [17]
7 P.pastoris   Shake flask (w - tunicamycin) 0.05 No [17]
8 H. polymorpha ~ 1100 Fermenter 80 No -