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Table 1 Neutralization (ID50) of subtype-A, B and C viruses by #254 plasma sample

From: A novel strategy for efficient production of anti-V3 human scFvs against HIV-1 clade C

Sr. No.

Virus

Tier

Subtype

ID50

1

92RW009

1

A

74

2

Q461

1

A

98

3

SF162

1

B

1296

4

JRCSF

1

B

103

5

Du156.12

2

C

206

6

ZM53M.PB12

2

C

<60

7

ZM109F.PB4

2

C

104

8

JRFL

2

B

<60

9

RHPA4259.7

2

B

446

10

TRO.11

2

B

162

  1. The cross neutralizing activities of plasma antibodies from HIV-1 infected drug naïve sample #254 against a panel of subtype-A, B, C tier 1 and 2 viruses indicated on left. The numerical values on the extreme right of table represent the mean 50% neutralization titers (ID50) defined as the reciprocal dilution of plasma which neutralized 50% of viral infection in the assay. For clarity, this information is coded; ID50> 1000 (Bold), ID50= 100-l000 (Bold Italic), ID50= 61–100 (Italic) and ID50<60, where 50% neutralization was not reached. Each experiment was performed at least two independent times and in duplicates.