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Figure 1 | BMC Biotechnology

Figure 1

From: Enhanced recombinant protein production and differential expression of molecular chaperones in sf-caspase-1-repressed stable cells after baculovirus infection

Figure 1

The apoptosis pathway in S. frugiperda cells. Apoptotic signals trigger the activation of initiator Sf-caspase-X in S. frugiperda cells. The Op-IAP and Sf-IAP suppress the activation of Sf-caspase-X, which proteolytically activates downstream effector caspases, including Sf-caspase-1, by cleavage at the large-small subunit junction. The activated effector caspases can amplify this processing and different steps are inhibited by P49 and P35.

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