Figure 8From: Selective delivery of interleukine-1 receptor antagonist to inflamed joint by albumin fusionRepresentative ankle joints histology in mice among the experimental groups (1), normal control; (2) and (3), CIA plus saline; (4), CIA plus HSA; (5) CIA plus IL-1ra; (6) CIA plus the fusion protein. (a), synovial hyperplasia and exudation of inflammatory cells into the synovial space; (b), synovial hyperplasia, pannus formation, and erosion of bone and cartilage.Back to article page