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Figure 4 | BMC Biotechnology

Figure 4

From: Optimization of glutathione production in batch and fed-batch cultures by the wild-type and recombinant strains of the methylotrophic yeast Hansenula polymorphaDL-1

Figure 4

Growth and glutathione accumulation of H. polymorpha DL-1 recombinant strains at glucose-feeding fermenter cultivation. A - Dry cell weight (DCW); B, C - TIG (GSH+GSSGin) and TEG (GSH+GSSGex) concentrations, expressed in nmol/mg protein (B) and in mg/L culture medium (C) of H. polymorpha DL-1 wild type (rhombus) and recombinant strains: MOXp-GSH2 (cycle), mcGSH2 (cross), mcMET4 (triangle) at fed-batch cultivation in glucose minimal medium under condition of DO-stat 30%. TEG concentration is indicated with open symbols (C). Values shown are the means of two independent determinations.

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BMC Biotechnology

ISSN: 1472-6750

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