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Table 1 Analysis of the binding properties of PfMSP119-specific human IgA (C1), human IgG1 (C1) and mouse mAb 12.10 to immobilized GST-PfMSP119 by SPR.

From: The generation and evaluation of recombinant human IgA specific for Plasmodium falciparum merozoite surface protein 1-19 (PfMSP119)

 

Kass

Kdiss

Kd

 

(M-1 sec-1)

(sec-1)

(M)

mAb 12.10

5.37 × 105

5.5 × 10-6

1 × 10-11

IgG1 (C1)

4.4 × 103

1.0 × 10-4

2.3 × 10-8

IgA (C1)

6.5 × 103

1.7 × 10-4

2.6 × 10-8

  1. (Kd = Kdiss/Kass)
  2. Methodology described in refs [3, 13].
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BMC Biotechnology

ISSN: 1472-6750

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