Figure 3From: Systematic cross-validation of 454 sequencing and pyrosequencing for the exact quantification of DNA methylation patterns with single CpG resolutionCross-validation of 454 sequencing and conventional pyrosequencing: individual methylation levels. Comparison of the methylation levels of individual CpG dinucleotides of selected genes in selected samples: Even samples with a very heterogeneous methylation pattern (e.g. p16INK4A) display an excellent congruence. (â ) 454 sequencing, (â) pyrosequencingBack to article page