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Table 1 Comparison of different methods for purification of LVs.

From: Highly efficient concentration of lenti- and retroviral vector preparations by membrane adsorbers and ultrafiltration

  SN elution concentrate
purification method volume
[ml]
IP/ml
(± SEM)
IP
(± SEM)
volume
[ml]
IP/ml
(± SEM)
IP
(± SEM)
volume
[ml]
IP/ml
(± SEM)
IP
(± SEM)
MA/UF
(n = 7)
40 3.0 × 107
(± 4.7 × 106)
1.2 × 109
(± 1.8 × 108)
4.7
(± 0.2)
1.3 × 108
(± 2.2 × 107)
6.2 × 108
(± 9.5 × 107)
355
(± 32)
1.8 × 109
(± 4.0 × 108)
5.8 × 108
(± 1.2 × 108)
UC
(n = 3)
40 1.2 × 107
(± 1.3 × 106)
4.7 × 108
(4.8 ± × 107)
  -   327
(± 18)
6.8 × 108
(± 8.9 × 107)
2.1 × 108
(± 2.1 × 107)
MA/UF
(n = 6)
500 1.4 × 107
(± 8.6 × 105)
7.1 × 109
(± 5.2 × 108)
25.8
(± 0.2)
1.5 × 108
(± 3.5 × 107)
2.7 × 109
(± 3.5 × 108)
1064
(± 118)
2.7 × 109
(± 3.7 × 108)
2.8 × 109
(± 5.0 × 108)
UC
(n = 3)
500 2.5 × 107
(± 6.6 × 106)
1.3 × 1010
(± 3.3 × 109)
  -   776
(± 152)
6.1 × 109
(± 1.1 × 109)
4.6 × 109
(± 1.1 × 109)
MA/UF
(n = 3)
1000 1.8 × 107
(± 4.9 × 106)
1.9 × 1010
(± 5.2 × 109)
40.6
(± 0.7)
1.7 × 108
(± 4.8 × 107)
7.0 × 109
(± 1.9 × 109)
1510
(± 220)
5.4 × 109
(± 1.8 × 109)
8.6 × 109
(± 3.6 × 109)