Table 4 A list of cancer-related genes targeted by iggyback or Tol2
Transposon | Target ID | Sequence | Targeted Cancer Gene | Annotation |
|---|---|---|---|---|
piggyBac | B102-2 | TTAAATAAAAAAGAACAGATATTTGAAATTGGCTGTTG | GPHN | gephyrin |
| Â | B107-3 | TTAATGATTCTTTCCATTTCTTTTATTCTTTTCCTAGC | HHEX | hematopoietically expressed homeobox |
| Â | B27-3 | TTAATAGAAAGGAAGGGACCATGTTTAACATAAATGCT | POU6F2 | POU class 6 homeobox 2 |
| Â | B38-4 | TTAAATAAAAAAGAACAGATATTTGAAATTGGCTGTTG | GPHN | gephyrin |
| Â | B63-1 | TTAAGTTTTCAGTGGCTGAAAGTTGGCAGTCTGAAAAA | ARF4 | ADP-ribosylation factor 4 |
| Â | B81-1 | TTAAGTGCTTTTGGCTGTTTTCCCAAACATCCAGACAT | SMAD5 | SMAD family member 5 |
Tol2 | T12-2 | GGTAGGAGTTATCTGAGTCAGGCCTGCCCTTGGCTTGG | SPECC1 | cytospin B |
| Â | T121-1 | CTCCTGGGTGACCCTCGCCTGAGCCTCCTGGCCCTTCC | RAB40B | RAB40B, member RAS oncogene family |
| Â | T102-4 | GACACAAACACACACATGCTATACCTTTGTATTACACT | TCF4 | transcription factor 4 |
| Â | T124-4 | GCGGCTGTCCTCCAGCAACAGGTGCACATTCCCGGGCT | TNK1 | tyrosine kinase, non-receptor |
| Â | T130-2 | CAAATAAATGAATGTTATGAATTTTTGAGGGTAGGAAA | SEMA3C | sema domain, immunoglobulin domain (Ig), (semaphorin) 3C precursor |
| Â | T137-3 | AAAGAGAGGCCCAATCCTGTGGAGTGAGTCACTGGGGG | ALPL | alkaline phosphatase, liver/bone/kidney |
| Â | T137-4 | ATTTTCTGTCTGCTCTTTGGTCACTTCCCATTCTTTTT | PARD3 | par-3 partitioning defective 3 homolog (C. elegans) |
| Â | T157-4 | TTTATTTGTCCTGCACTTATGAAGCATAGTTTGGCAGG | PGR | progesterone receptor |
| Â | T165-1 | GAAACCGGCGAAAAGGTTAGCTGTCGCTGGCTAGTATT | RASSF3 | Ras association (RalGDS/AF-6) domain family member 3 |
| Â | T22-1 | TTCCTAAGCTACAATAAACCACATATGAAAAACTAAAG | HD | huntingtin |
| Â | T26-1 | AGCCTGAGTAAAATAGTGAGACTCTGTTTCTGCAAAAC | LRP1B | low density lipoprotein-related protein 1B |
| Â | T43-3 | TCTGGAAGGTGAGGCAGACGTGCCCACCGCCTCCATGC | HLXB9 | motor neuron and pancreas homeobox 1 |
| Â | T91-4 | TTCAGGGGGTGTGTTGGAGGGGAATCGCCGGCCTGCCT | IHH | Indian hedgehog homolog (Drosophila) |
| Â | TB7-5 | AATTTATCCATTTCTTCTAGATTTTCTAGTTTATTCGC | FKBP1A | FK506 binding protein 1A, 12kDa |
| Â | TB70-1 | GTGCACACACTCACTCTCTCTTTCTCCTTCAGATAATA | FOXP1 | forkhead box P1 |
| Â | TB77-2 | CCCCTCACCCTCGGACCCTTCACCGCGACCCCCGCGCC | RANBP9 | RAN binding protein 9 |
| Â | TB81-1 | TGCAGTACAGTGCGGGGGGAAAAAAACAACAGCAAAAG | EGF | epidermal growth factor (beta-urogastrone) |