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Figure 4 | BMC Biotechnology

Figure 4

From: Combining M-FISH and Quantum Dot technology for fast chromosomal assignment of transgenic insertions

Figure 4

Combined M-FISH analysis and QD detection allows chromosomal assignment of transgenic insertions in a rat model. Aligning the QD 585 detection image (A) and M-FISH metaphase spread image (B) again allows identification of chromosome 6 (pseudo-colored in yellow by the M-FISH karyotyping software) as the chromosome holding the transgenic insertion and confirms this specific rat model to be hemizygous for the insertion (transgene presents only on one of the two homologs).

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