Skip to main content
Figure 1 | BMC Biotechnology

Figure 1

From: Isolation of a nanomolar scFv inhibiting the endopeptidase activity of botulinum toxin A, by single-round panning of an immune phage-displayed library of macaque origin

Figure 1

Neutralisation of 10LD 50 /ml BoNT/A with scFv 2H8. 2H8 reacted with BoNT/A1 (43.5 pg/ml; 10 LD50/ml) and showed dose dependent inhibition of endopeptidase activity in vitro. The negative controls (43RCA and 38RCA), directed against ricin toxin, showed no inhibition at equivalent protein concentration. Results are mean with range (n = 2). BoNT A1 toxin control (10 LD50/ml): broken line. Buffer control: dotted line.

Back to article page

BMC Biotechnology

ISSN: 1472-6750

Contact us