Table 1 Chimeric constructs with the L1ΔC22 regions deleted and the influenza epitopes inserted.
Chimeric variant | L1ΔC22 modifications | ||||
|---|---|---|---|---|---|
| Â | Structural function | Deleted sequence | aa position | Inserted Influenza M2e sequence | aa position |
ChiM2e2-24_h4 | h4 | LEDTYRFVTQAI | 440-451 | SLLTEVETPTRNEWECKCIDSSD | 440-462 |
ChiM2e2-9_h4 | h4 | LEDTYRFVTQAI | 440-451 | SLLTEVET | 440-447 |
ChiM2e2-24_c | coil between h4 and β-J | HTPPAPKEDDPLKK | 456-469 | SLLTEVETPTRNEWECKCIDSSD | 456-478 |
ChiM2e2-9_c | coil between h4 and β-J | HTPPAPKEDDPLKK | 456-469 | SLLTEVET | 456-463 |