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Table 2 Assessment of the cytokine concentrations (pg/ml) at 12, 24 and 48 hours post gas vesicle addition.

From: SIVsm Tat, Rev, and Nef1: functional characteristics of r-GV internalization on isotypes, cytokines, and intracellular degradation

 

IL-10 (pg/ml)

IL-12 (pg/ml)

IL-18 (pg/ml)

 

12 h

24 h

48 h

12 h

24 h

48 h

12 h

24 h

48 h

Media †

29.791

32.794

31.677

7.276

10.908

13

17.037

15.163

10.606

NRC-1 ‡

27.037

28.712

28.774

11.795

9.643

13.086

72.51

76.747

78.739

Tat

185.311

28.476

31.404

52.680

14.048

13.653

85.332

115.166

106.121

Rev

147.218

67.513

37.792

9.959

10.693

19.830

99.325

56.274

55.549

Nef1

31.739

537.384

168.622

8.675

6.498

54.730

68.855

68.935

72.456

  1. † As detailed in the methods, macrophage monolayers received media only.
  2. ‡ Control wells received the wild type gas vesicles NRC-1.