Table 2 Senescence-Related Genes with Significant Differences in Gene Expression Levels in Senescent vs. Non-Senescent Annulus Cells
Gene Name | Ratio/Fold Change | Direction | P value | Gene Identifier |
|---|---|---|---|---|
RB-associated KRAB zinc finger | 1.51 | Up | 0.022 | AW138835 |
Discoidin, CUB and LCCL domain containing protein 2 | 1.47 | Up | 0.038 | AW300360 |
p38 (p38 MAP kinase; MPAK14) | 1.37 | Up | 0.029 | AF218033 |
Inhibitor of growth family, member 5 (p28ING5) | 1.18 | Up | 0.046 | BC005370 |
Growth arrest and DNA-damage-inducible, beta | 1.06 | Up | 0.040 | AV658684 |
Somatostatin receptor 3 | 1.03 | Up | 0.048 | NM_001051 |
Interferon induced transmembrane protein 1 (9-27) | 1.08 | Up | 0.038 | NM_003641 |
Sphingosine-1-phosphate receptor 2 | 1.38 | Up | 0.046 | NM_004230 |
Cyclin-dependent kinase 8 (CDK8) | 1.12 | Down | 0.049 | NM_001260 |
Nitric oxide synthase 1 | 1.06 | Down | 0.017 | U31466 |
Heat shock 70 kDa protein 6 (HSP70B) | 1.11 | Down | 0.020 | X51757 |