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Figure 7 | BMC Biotechnology

Figure 7

From: Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell-mediated chromosome transfer

Figure 7

Detection of transferred HAC in microcell hybrids by FISH. The transferred HAC (arrow) is delineated by fluorescence in situ hybridization using an alphoid satellite probe derived from human chromosome 21. The alphoid satellite probe (red) detects endogenous chromosomes 13 and 21(arrowheads), in addition to the HAC, due to their sequence similarity. Results from HT1080, hiMSC, or HFL-1 cells were placed on left, center, and right, respectively.

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