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Figure 3 | BMC Biotechnology

Figure 3

From: Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell-mediated chromosome transfer

Figure 3

Genetically engineered CHO cells can produce fusogenic microcells. (a) Microcells were prepared from the MV-F/H-transfected CHO cells and placed on HT1080 cells. Photographs were taken after 24 h. A few recipient cells emitting fluorescence were observed. (b) HT1080 cells that had been in contact with the microcells were selected for 14 days with Blasticidin and drug-resistant colonies were photographed. These cells expressed GFP but not DsRed, suggesting retention of the HAC and elimination of MV-F/H-tagged host chromosomes. Photographs were taken under phase contrast (left) or fluorescence (center and right) microscopic conditions. Scale bar, 10 μm.

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BMC Biotechnology

ISSN: 1472-6750

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