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Figure 2 | BMC Biotechnology

Figure 2

From: Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell-mediated chromosome transfer

Figure 2

Genetically engineered CHO cells can fuse with human cells. G418-resistant CHO cells (a) expressed the GFP (b) and/or the fluorescent marker DsRed (c). An equal number of the CHO cells (a) and HT1080 cells (d) were mixed, and photographed 3 days later (f, g, h). Similar to the MV-F/H-transfected HT1080 cells (e), large multinucleated syncytia were observed (f). Syncytia made by heterofusion of CHO and HT1080 expressed GFP and DsRed fluorescence (g, h). The panels a, b, c and f, g, h show the same cell field, respectively. Scale bar, 10 μm. Photographs were taken under phase contrast (a,d,e,f) or fluorescence (b,c,g,h) microscopic conditions.

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BMC Biotechnology

ISSN: 1472-6750

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