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Table 4 Phenotypic description of the embryos treated at 24 hpf followed by automatic image acquisition.

From: Phenotypic analysis of images of zebrafish treated with Alzheimer's γ-secretase inhibitors

Cpd

Embryo Number

Conc.

Pigment

Tail

Trunk

DMSO

16

0.1%

normal

all straight

all straight

DAPT

14

50 μM

decreased

9/14 curved

9/14 curved

Gleevec

17

50 μM

normal

all straight

all straight

AD28

11

100 μM

normal

1/11 slightly curved

1/11 short

AD94

6

50 μM

3/6 lighter

all straight

all straight

AD95

8

50 μM

normal

5/8 bent

1/8 edema

AD115

9

10 μM

decreased around swim bladder

2/9 curved

5/9 edema

PTU

11

200 μM

Decreased

all straight

all straight