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Table 1 Criteria for a Partner Hit

From: A surrogate-based approach for post-genomic partner identification

1. Search gives an exact match of ≥ 5–7 amino acids or appearance of the

partner in at least 50% of the top cohort of any one search, and/or the

appearance of the same or related hits occurring in multiple searches.

2. Search matches an expected class of protein partners based on function,

cellular location or tissue/disease distribution.

3. Candidate produces a phenotype change when added into the

appropriate model system