From: A surrogate-based approach for post-genomic partner identification
1. Search gives an exact match of ≥ 5–7 amino acids or appearance of the |
partner in at least 50% of the top cohort of any one search, and/or the |
appearance of the same or related hits occurring in multiple searches. |
2. Search matches an expected class of protein partners based on function, |
cellular location or tissue/disease distribution. |
3. Candidate produces a phenotype change when added into the |
appropriate model system |