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Figure 5 | BMC Biotechnology

Figure 5

From: A surrogate-based approach for post-genomic partner identification

Figure 5

Alignment of the TNFβ surrogate peptide KcB7 with its cognate receptor TNFR1 (p55). Peptide KcB7 was isolated by panning TNFβ. The peptide has the sequence RKEMGGGGGPGWSENLFQ and a BLASTp search revealed identity to amino acids 77–81 (RKEMG) and amino acids 107–113 (WSENLFQ) on TNFR1 (p55). RKEMG is involved in binding of TNFR1 to the A subunit of TNFβ while WSENL binds to several amino acids in the C subunit of TNFβ

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