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Table 1 Summary of GS-E induction of luciferase activity in clone MBT-2 + RHeoSwitch #2 + pG5-luc – 5B3

From: Manipulation of gene expression by an ecdysone-inducible gene switch in tumor xenografts

Experiment RLU 1^ RLU 1   RLU 2' RLU 2   RLU1/RLU2 RLU 1/RLU2  
  CON GS-E T/C CON GS-E T/C CON GS-E T/C
A 4457* 992343 222.6 543227 678517 1.2 0.01 1.46 178.3
B 4123 948272 230.0 579818 709519 1.2 0.01 1.34 188.0
C 4771 982058 205.8 658164 823060 1.3 0.01 1.19 164.6
D 3915 597044 152.5 537789 720480 1.3 0.01 0.83 113.8
E 1757 350947 199.7 75614 95031 1.3 0.02 3.69 158.9
F 1405 314349 223.7 232147 300061 1.3 0.01 1.05 173.1
G 1343 234858 174.9 174883 207357 1.2 0.01 1.13 147.5
H 3958 737902 186.4 197599 227480 1.2 0.02 3.24 161.9
I 3822 710260 185.8 209591 251976 1.2 0.02 2.82 154.6
J 3714 692231 186.4 218191 259666 1.2 0.02 2.67 156.6
   Mean 196.8   Mean 1.2   Mean 159.7
   SD 24.4   SD 0.1   SD 20.1
   N 10   N 10   N 10
  1. CON: control carrier applied only Only 48 hour time-points displayed in this summary ^RLU1 is expression of firefly luciferase from the inducible promoter 'RLU2 is expression of Renilla luciferase from the constitutive TK promoter *All data points shown are the average from duplicate or triplicate samples